منابع مشابه
Neurophysiology of Nicotine Addiction.
Tobacco use is a major health problem, and nicotine is the main addictive component. Nicotine binds to nicotinic acetylcholine receptors (nAChR) to produce its initial effects. The nAChRs subtypes are composed of five subunits that can form in numerous combinations with varied functional and pharmacological characteristics. Diverse psychopharmacological effects contribute to the overall process...
متن کاملCocaine addiction: psychology and neurophysiology.
Cocaine was considered incapable of producing dependence in 1980 but was recently proclaimed the drug of greatest national health concern. Recent clinical and preclinical investigations demonstrate that cocaine produces unique abuse and withdrawal patterns that differ from those of other major abused drugs and suggest that long-term cocaine abuse produces neurophysiological alterations in speci...
متن کاملManaging nicotine addiction.
Nicotine addiction has been identified as the primary contributor to continued widespread tobacco use worldwide. Although the health benefits of smoking cessation are well publicized, few smokers successfully quit on a long-term basis. A number of pharmacological agents have been shown to approximately double long-term smoking cessation rates and have, therefore, been recommended as first-line ...
متن کاملAssessment Scales for Nicotine Addiction
Cigarette smoking is still a major cause of many preventable diseases [1]. The pharmacologic effect of nicotine plays a crucial role in tobacco addiction [1,2]. When issues around tobacco use are considered, “nicotine addiction” can be regarded as a roadblock that needs to be overcome. The importance of nicotine in maintaining smoking and in cessation difficulty has been well acknowledged [3]. ...
متن کاملSynaptic Plasticity and Nicotine Addiction
Nicotine, the main addictive component of tobacco, activates and desensitizes nicotinic acetylcholine receptors (nAChRs). In that way, nicotine alters normal nicotinic cholinergic functions. Among the myriad of psychopharmacological effects that underlie the addiction process, nicotine influences nAChR participation in synaptic plasticity. This influence has particular importance in the mesocor...
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ژورنال
عنوان ژورنال: Journal of Addiction Research & Therapy
سال: 2012
ISSN: 2155-6105
DOI: 10.4172/2155-6105.s1-001